Chapter 3

What the evidence says


An honest overview of where the research is strong, where it's promising and where it's thin.

In progressLast updated September 26, 2026

This chapter is being written. Every chapter is reviewed against the published research before it goes live.

What this chapter will cover

  • How to read a study: RCTs, open-label trials, meta-analyses
  • Evidence strength by substance
  • Common limitations: blinding, small samples, expectancy
  • How we grade evidence on this site