Conditions
Evidence by condition
For each condition: every relevant study in the library, and a plain-language verdict on how strong the evidence is today.
Depression and treatment-resistant depression
What research shows on ketamine, esketamine, psilocybin, DMT and 5-MeO-DMT for depression, including depression that hasn't responded to treatment.
PTSD
What the research shows about MDMA-assisted therapy, ketamine and other psychedelic treatments for post-traumatic stress disorder.
Chronic pain
What the research shows about ketamine infusions and emerging psychedelic research for chronic and neuropathic pain.
Alcohol and substance use
What the research shows about psilocybin, ketamine, LSD, 5-MeO-DMT and ibogaine for alcohol use disorder and other addictions.
Anxiety and end-of-life distress
What the research shows about psilocybin and LSD for anxiety, including anxiety and depression in people facing serious illness.
Suicidal thoughts
What the research shows about ketamine and esketamine for rapid reduction of suicidal thoughts, and what isn't known.