Evidence
Evidence by condition
For each condition: every relevant study in the library, and a plain-language verdict on how strong the evidence is today.
Depression and treatment-resistant depression
Studies of ketamine, esketamine and psilocybin for major depression, including depression that hasn't responded to other treatments.
PTSD
Research on MDMA-assisted therapy, ketamine and psilocybin for post-traumatic stress disorder.
Chronic pain
Ketamine infusions and emerging psychedelic research for chronic and neuropathic pain.
Alcohol and substance use
Trials of psilocybin, ketamine and other compounds for alcohol use disorder and other addictions.
Anxiety and end-of-life distress
Research on psilocybin for anxiety and depression in people facing serious illness.
Suicidal thoughts
What the research shows about rapid-acting treatments like ketamine for suicidal ideation.